| Bootstrap | 1,417,753 | https://getbootstrap.com |
| ZURB Foundation | 108,058 | https://foundation.zurb.com |
| UIKit | 65,796 | https://getuikit.com |
| Tailwind CSS | 21,738 | https://tailwindcss.com/ |
| Material Design Lite | 6,853 | https://getmdl.io |
| Pure CSS | 6,778 | https://purecss.io |
| MDBootstrap | 4,504 | https://mdbootstrap.com |
| Ant Design | 4,482 | https://ant.design |
| Semantic UI | 3,563 | https://semantic-ui.com/ |
| shadcn-svelte | 2,784 | https://www.shadcn-svelte.com |
| GOV.UK Frontend | 1,679 | https://design-system.service.gov.uk/ |
| Materialize CSS | 1,659 | https://materializecss.com |
| USWDS | 1,357 | https://designsystem.digital.gov |
| Flowbite | 764 | https://github.com/themesberg/flowbite |
| Shoelace | 598 | https://shoelace.style |
| Flat UI | 535 | https://designmodo.github.io/Flat-UI/ |
| Kendo UI | 471 | https://www.telerik.com/kendo-ui |
| Preline UI | 365 | https://preline.co |
| Milligram | 358 | https://milligram.io |
| Element UI | 309 | https://element.eleme.io/ |