| Bootstrap | 798,978 | https://getbootstrap.com |
| ZURB Foundation | 61,066 | https://foundation.zurb.com |
| UIKit | 34,292 | https://getuikit.com |
| Tailwind CSS | 11,244 | https://tailwindcss.com/ |
| Pure CSS | 3,826 | https://purecss.io |
| Material Design Lite | 3,625 | https://getmdl.io |
| shadcn-svelte | 2,784 | https://www.shadcn-svelte.com |
| Ant Design | 2,781 | https://ant.design |
| MDBootstrap | 2,181 | https://mdbootstrap.com |
| Semantic UI | 2,161 | https://semantic-ui.com/ |
| GOV.UK Frontend | 1,163 | https://design-system.service.gov.uk/ |
| USWDS | 1,067 | https://designsystem.digital.gov |
| Materialize CSS | 901 | https://materializecss.com |
| Flowbite | 445 | https://github.com/themesberg/flowbite |
| Flat UI | 347 | https://designmodo.github.io/Flat-UI/ |
| Shoelace | 321 | https://shoelace.style |
| Element UI | 309 | https://element.eleme.io/ |
| Kendo UI | 240 | https://www.telerik.com/kendo-ui |
| Milligram | 230 | https://milligram.io |
| IBM Carbon Design System | 196 | https://carbondesignsystem.com |